MDMA literature reviewFri 28 September 2018
The takeaway is that MDMA is quite dangerous, though as always more research is needed:
Unfortunately the evidence is very strongly on the side of “dangerous”.
Retrospective studies of long term [MDMA] users show cognitive deficits not found in other drug users, while animal studies show brain damage and inconsistent cognitive deficits.
The one bright spot is the MAPS study, which reported no drop in cognitive function after a therapeutic dose of MDMA, but we’ll talk about the problems with that later.